原创《肺炎克雷伯菌致社区感染和医院感染的耐药性调查》：本文关于雷伯论文范文,可以做为相关论文参考文献,与写作提纲思路参考。
[摘 要] 目的 比較医院感染和社区感染肺炎克雷伯菌的耐药性差异,为指导临床合理用药提供依据. 方法 收集2015年1月～2016年12月住院患者不同标本的肺炎克雷伯菌共1393株,进行耐药性监测,并判断是否为医院感染,同时分析社区感染与医院感染的耐药性差异.结果 1393株肺炎克雷伯菌中,共检出产ESBLs肺炎克雷伯菌176株,检出率为12.63%,产ESBLs肺炎克雷伯菌对抗菌药物的耐药性普遍高于非产ESBLs；在肺炎克雷伯菌（ESBLs-）方面,医院感染的菌株数对哌拉西林等四种抗菌药的耐药率低于社区感染,而医院感染的肺炎克雷伯菌对头孢他啶等五种抗菌药的耐药率高于社区感染；在肺炎克雷伯菌（ESBLs+）方面,医院感染菌株对替苄西林等两种抗菌药的耐药率低于社区感染,而医院感染的菌株对复方新诺明等两种抗菌药的耐药率高于社区感染,差异有统计学意义（P<0.05）. 结论 无论是社区感染还是医院感染的肺炎克雷伯菌,特别是产ESBLs的肺炎克雷伯菌,对多种抗菌药物的具有高耐药率,医院应加强其所致医院感染的监测,并积极采取有效的控制措施.
[关键词] 肺炎克雷伯菌；医院感染；社区感染；耐药性
[中图分类号] R446.5 [文献标识码] B [文章编号] 1673-9701（2018）08-0122-03
Investigation on drug resistance of community-acquired and hospital-acquired infections caused by Klebsiella pneumoniae
XIONG Kai SHI Yu
Medical record statistical division, The Second Clinical Medical School of Inner Mongolia University for the Nationalities,Inner Mongolia Forestry General Hospital,Yakeshi 022150, China
[Abstract] Objective To compare the drug resistance of Klebsiella pneumoniae between hospital-required infection and community-acquired infection, in order to provide basis for clinical rational drug use. Methods A total of 1393 strains of Klebsiella pneumoniae were collected from different samples of patients who were hospitalized from January 2015 to December 2016, in order to monitor the drug resistance and determine whether they were hospital-acquired infections. The differences in drug resistance between community and hospital acquired infections were analyzed. Results Among 1393 strains of Klebsiella pneumoniae, 176 strains of Klebsiella pneumoniae producing ESBLs were detected, the detection rate was 12.63%. The ESBLs-producing Klebsiella pneumoniae strains were generally more resistant to antibiotics than non-ESBLs-producing strains. In the case of Klebsiella pneumoniae（ESBLs-）, the drug resistance rates of hospital-acquired infections to four antibacterials, such as piperacillin, were lower than that of community-acquired infections, whereas the drug resistance rates of hospital-acquired Klebsiella pneumoniae to five antibacterial drugs including ceftazidime were higher than that of community-acquired infection. In the case of Klebsiella pneumoniae （ESBLs+）, the drug resistance rates of hospital-acquired infections to two antibacterials such as ticarcillin were lower than that of community-based ones, while the resistance rates to two antibacterials including cotrimoxazole were higher than that of community infection（P<0.05）. Conclusion lebsiella pneumoniae, especially ESBLs-producing Klebsiella pneumoniae, both community-acquired and hospital-acquired, have a high rate of drug resistance to a wide range of antibacterial agents. The hospital-acquired infections should be monitored and treated actively through effective control measures.
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结论：肺炎克雷伯菌致社区感染和医院感染的耐药性调查为关于对写作雷伯论文范文与课题研究的大学硕士、相关本科毕业论文雷伯论文开题报告范文和相关文献综述及职称论文参考文献资料下载有帮助。
