关于老年痴呆症论文范文资料与中西医治疗老年痴呆症的临床疗效与安全性有关论文参考文献-论文写作网

《中西医治疗老年痴呆症的临床疗效与安全性》：本论文可用于老年痴呆症论文范文参考下载，老年痴呆症相关论文写作参考研究。

【摘要】目的探讨中西医治疗老年痴呆症的临床疗效和安全性.方法 80例老年痴呆症患者, 采用随机数字法分为对照组和观察组, 各40例.两组患者均接受常规对症治疗, 在此基础上, 对照组使用吡拉西坦脑蛋白水解物片治疗, 观察组在对照组基础上联用中药方剂补肾益气治呆汤方治疗.比较两组的治疗效果.结果观察组患者治疗总有效率为95.0%, 高于对照组的67.5%, 差异具有统计学意义（P<0.05）.治疗后观察组患者简易智能精神状态检查量表（MMSE）评分、巴氏指数（BI）评分、认知功能及记忆力评分均高于对照组, Blessed痴呆量表评分低于对照组, 差异均具有统计学意义（P<0.05）.观察组不良反应发生率为7.5%, 与对照组的5.0%比较差异无统计学意义（P>0.05）.结论中西医结合治疗老年痴呆症患者安全有效, 值得在临床推广应用.

【关键词】老年痴呆症；吡拉西坦；补肾益气治呆汤

DOI：10.14163/j.cnki.11-5547/r.2017.27.017

【Abstract】 Objective To investigate the clinical efficacy and safety of Chinese and Western medicine in the treatment of Alzheimer’s disease. Methods A total of 80 Alzheimer’s disease patients were divided by random number method into control group and observation group, with 40 cases in each group. Both groups received coventional symptomatic treatment. The control group was also treated with piracetam brain protein hydrolysate, and the observation group was treated with Chinese medicinal formulae of Bushen Yiqi Zhidai decoction on the basis of the control group. Treatment effect in two groups was compared. Results The observation group had higher treatment effective rate as 95.0% than 67.5% in the control group, and the difference was statistically significant （P<0.05）. After treatment, the observation group had higher mini mental state examination （MMSE） scale, Barthel index （BI） score, cognitive function and memory score than the control group, and lower Blessed dementia scale score than the control group. The difference was statistically significant （P<0.05）. The observation group had no statistically significant difference in incidence of adverse reactions as 7.5%, comparing with 5.0% in the control group （P>0.05）. Conclusion It is safe and effective for the treatment of Alzheimer’s disease patients with integrated traditional Chinese and Western medicine, and it is worthy of clinical popularization and application.

【Key words】 Alzheimer’s disease； Piracetam； Bushen Yiqi Zhidai decoction

老年癡呆症即阿尔茨海默病（AD）, 是临床常见的一种以神经系统退行性变的神经系统疾病, 该病发展隐匿, 病情呈进展性发展, 导致患者记忆障碍、失语、失用、失认、视空间技能损害、执行功能障碍以及人格和行为改变等, 即全面性痴呆, 尤其以老年患者常见, 故而称老年痴呆[1, 2].目前, 临床治疗主要以控制并抵抗伴发的精神疾病为治标, 同时使用益智药物或改善认知功能的药物为治本, 治标联合治标为治疗目的, 但临床上西医治疗较差.本研究采用中西医结合治疗老年痴呆症, 取得了一定的疗效, 现报告如下.

1 资料与方法

1. 1 一般资料选取本院2015年2月～2017年2月收治的老年痴呆症患者80例为本研究入组研究目标, 并采用随机数字法将患者分为对照组和观察组, 各40例.对照组男23例, 女17例；年龄60～85岁, 平均年龄（70.6±5.2）岁；病程2～15年, 平均病程（5.4±3.2）年.观察组男25例, 女15例；年龄60～85岁, 平均年龄（71.1±5.6）岁；病程2～15年, 平均病程（5.5±3.2）年.两组患者年龄、性别等一般资料比较差异均无统计学意义（P>0.05）, 具有可比性.本研究方案设计通过院*委员会的审核批准.

老年痴呆症论文参考资料：

结论：中西医治疗老年痴呆症的临床疗效与安全性为关于本文可作为老年痴呆症方面的大学硕士与本科毕业论文老年痴呆症论文开题报告范文和职称论文论文写作参考文献下载。