原创《阿米替林联合多潘立酮治疗功能性消化不良的疗效分析》：本论文为您写阿米替林毕业论文范文和职称论文提供相关论文参考文献，可免费下载。
DOI：10.16662/j.cnki.1674-0742.2017.16.105
[摘 要] 目的 分析阿米替林联合多潘立酮治疗功能性消化不良的疗效与安全性.方法 2015年1月—2016年7月,方便选取门诊入选患者120例,采用随机数字表达法分组,对照组、观察组各入组60例.均给予多潘立酮,观察组联合阿米替林,持续8周.对比治疗前后HADM、消化道症状积分与疗效.结果 观察组未见退出者,对照组退出1例.治疗后,观察组HAMD、消化道症状积分分别为（5.6±1.1）分、（2.4±1.5）分低于对照组（10.4±3.1）分、（8.6±3.9）分,差异有统计学意义（P<0.05）.观察组痊愈率、愈显率分别为55.0%、85.0%高于对照组18.6%、62.7%,观察组无效率0.0%低于对照组16.9%,差异有统计学意义（P<0.05）.观察组出现1例口干,观察组6个月复发率3.33%低于对照组27.12%,差异有统计学意义（P<0.05）.结论 阿米替林联合多潘立酮治疗功能性消化不良可增进疗效.
[关键词] 功能性消化不良；阿米替林；多潘立酮
[中图分类号] R57 [文献标识码] A [文章编号] 1674-0742（2017）06（a）-0105-03
Analysis of Curative Effect of Amitriptyline and Repeated Li Ketone in Treatment of Functional Dyspepsia
ZHANG Rui
Outpatient Department, Kurle 273 Hospital of Bayingolin Mongol Autonomous Prefecture,Korla, Xinjiang, 841000 China
[Abstract] Objective To analyze the curative effect and safety of amitriptyline and repeated li ketone in treatment of functional dyspepsia. Methods 120 cases of outpatients from January 2015 to July 2016 were convenient selected and randomly divided into two groups with 60 cases in each, both groups were treated with repeated li ketone, while the observation group were treated with amitriptyline for the consecutive 8 weeks, and the HADM, gastrointestinal symptom integral and curative effect before and after treatment were compared. Results There were no bolters in the observation group and there was 1 bolter in the control group, after treatment, the HAMD and gastrointestinal symptom integral in the observation group were lower than those in the control group[（5.6±1.1）points,（2.4±1.5）points vs （10.4±3.1）points,（8.6±3.9）points], and the differences were statistically significant（P<0.05）, and the cure rate and cured and markedly effective rate in the observation group were higher than those in the control group（55.0%,85.0% vs 18.6%,62.7%）, and the ineffective rate in the observation group was lower than that in the control group（0.0% vs 16.9%）, and the difference was statistically significant（P<0.05）, in the observation group, there was 1 case with dry month, and the 6-month recurrence rate in the observation group was lower than that in the control group（3.33% vs 27.12%）, and the differences were statistically significant（P<0.05）. Conclusion The amitriptyline and repeated li ketone in treatment of functional dyspepsia can improve the curative effect.
[Key words] Functional dyspepsia； Amitriptyline； Repeated li ketone
功能性消化不良（functional dyspepsia,FD）是最常見的消化性系统疾病[1].功能性消化不良的发病机制较复杂,其中心理因素在疾病发生、进展中发挥重要作用,负面情绪会引起脑-肠轴调控失调,从而引起消化不良,与此同时消化不良症状会成为新的心理应激源,加重心理负担,形成恶性循环[2].针对伴严重负面情绪如重度抑郁的功能性消化不良,给予抗抑郁药物非常必要,但对于中度抑郁功能性消化不良,是否需要采用抗抑郁药物尚存在争议[3].阿米替林是一种常用的抗抑郁药物,疗效与黛力新、艾司西酞普兰相近,该次研究采用对照研究,以2015年1月—2016年7月入选功能性消化不良患者120例入组,分析阿米替林联合多潘立酮治疗功能性消化不良的临床疗效与安全性,现报道如下.
阿米替林论文参考资料：
结论：阿米替林联合多潘立酮治疗功能性消化不良的疗效分析为关于本文可作为阿米替林方面的大学硕士与本科毕业论文阿米替林论文开题报告范文和职称论文论文写作参考文献下载。
