原创《肝硬化并上消化道出血临床诊治分析》：这篇上消化道出血论文范文为免费优秀学术论文范文,可用于相关写作参考。
[摘 要] 目的 探析对肝硬化合并上消化道出血患者以奥曲肽联合奥美拉唑治疗的临床效果.方法 方便选取该院2013年1月—2016年12月期间收治的126例肝硬化合并上消化道出血患者,将其随机分为研究组和对照组,各63例,对照组以垂体后叶素治疗,研究组以奥曲肽联合奥美拉唑治疗,比较两组治疗效果及止血时间、住院时间等.结果 研究组总有效率92.06%和对照组比较,差异有统计学意义（P<0.05）；研究组平均止血时间（18.8±3.8）h、住院时间（5.8±2.1）d与对照组比较,差异有统计学意义（P<0.05）；研究组再出血率6.35%与对照组比较差异有统计学意义（P<0.05）；研究组不良反应率0.00%,对照组31.75%,差异有统计学意义（P<0.05）.结论 对肝硬化合并上消化道出血患者以奥曲肽联合奥美拉唑治疗的临床效果确切,安全性好,值得临床推广.
[关键词] 肝硬化；合并上消化道出血；奥曲肽
[中图分类号] R445 [文献标识码] A [文章编号] 1674-0742（2017）07（c）-0041-03
[Abstract] Objective To study the clinical effect of Octreotide combined with omeprazole in treatment of patients with cirrhosis and upper gastrointestinal hemorrhage. Methods 126 cases of patients with cirrhosis and upper gastrointestinal hemorrhage admitted and treated in our hospital from January 2013 to December 2016 were convenient selected and randomly divided into two groups with 63 cases in each, the control group and the research group were respectively treated with hypophysin and octreotide combined with omeprazole, and the treatment effect, hemostasis time and length of stay were compared between the two groups. Results The total effective rate was 92.06%, and the difference in this index between the two groups was statistically significant（P<0.05）, and the average hemostasis time and length of stay in the research group were respectively （18.8±3.8）h and （5.8±2.1）d, and the differences in the two indexes between the two groups were statistically significant（P<0.05）, and the re-bleeding rate in the research group was 6.35%, and the difference between the two groups was statistically significant（P<0.05）, and the incidence rate of adverse reactions in the research group and in the control group was respectively 0.00% and 31.75%, and the difference was statistically significant（P<0.05）. Conclusion The clinical effect of octreotide combined with omeprazole in treatment of patients with cirrhosis and upper gastrointestinal hemorrhage is definite, and the safety is good, which is worth clinical promotion.
[Key words] Cirrhosis； Combined with upper gastrointestinal hemorrhage； Octreotide
肝硬化在臨床上属于常见病,该疾病为一种弥漫性、纤维性、进行性肝脏病变疾病,上消化道出血为其常见的严重并发症,出血量大,患者病死率高,非静脉曲张上消化道出血是患者出血的主要因素之一.对于肝硬化合并上消化道出血患者,传统治疗中常常采取垂体后叶素和三腔二囊管压迫止血,不过仅对于静脉曲张破裂出血效果比较好,对于非静脉曲张破裂出血疗效欠佳,因此,选择合适的治疗方案,对降低患者死亡率意义重大[1].为进一步探析对肝硬化合并上消化道出血患者以奥曲肽联合奥美拉唑治疗的临床效果,该文将2013年1月—2016年12月期间收治的126例肝硬化合并上消化道出血患者,作为研究对象,现报道如下.
1 资料和方法
1.1 一般资料
方便选取该院收治的126例肝硬化合并上消化道出血患者,将其随机分为研究组和对照组,各63例,研究组：男性31例,女性32例,年龄27～97岁,平均（60.3±7.4）岁,肝炎后肝硬化患者41例,酒精性肝硬化患者11例,胆源性肝硬化患者10例,血吸虫性肝硬化患者1例；对照组：男性32例,女性31例,年龄28～96岁,平均（61.2±6.9）岁,肝炎后肝硬化患者42例,酒精性肝硬化患者12例,胆源性肝硬化患者8例,血吸虫性肝硬化患者1例；所有患者在入院就诊24 h内均有呕血或黑便等征象.两组在一般资料上比较差异无统计学意义（P>0.05）.
上消化道出血论文参考资料：
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