原创《艾司西酞普兰和帕罗西汀治疗强迫症疗效比较》：本文是一篇关于帕罗西汀论文范文，可作为相关选题参考,和写作参考文献。
摘 要 目的：研究艾司西酞普兰和帕罗西汀治疗强迫症的疗效.方法：收集2015年2月—2017年2月收治的强迫症患者54例,随机分为对照组27例,采用帕罗西汀治疗,观察组27例,采用艾司西酞普兰治疗,两组均治疗8周.用强迫症评定量表和汉密尔顿抑郁量表对患者症状进行评分,比较两组治疗有效率和不良反应发生率.结果：观察组有效率为77.78%（21/27）,对照组有效率为74.07%（20/27）,组间差异无统计学意义（P>0.05）.治疗8周后,两组症状评分均较治疗前下降（P<0.05）,尤其在治疗第1周时,观察组评分下降较对照组更为明显（P<0.05）.观察组不良反应发生率为11.11%（3/27）,对照组不良反应发生率33.33%（9/27）,组间差异有统计学意义（P<0.05）.结论：强迫症患者应用艾司西酞普兰和帕罗西汀治疗效果均较好,但艾司西酞普兰用药起效更快,安全性更高,患者产生的不良反应更少,值得推广应用.
关键词 强迫症；艾司西酞普兰；帕罗西汀；用药效果
中图分类号：R749.7 文献标志码：A 文章编号：1006-1533（2017）18-0022-03
Comparison of the efficacy between escitalopram and paroxetine in the treatment of obsessive compulsive disorder
YAN Xinpeng, RAO Ying
（The Fifth Ward of Corelle Hospital, Zhangshu 331211, Jiangxi Province, China）
ABSTRACT Objective： To study the efficacy of escitalopram and paroxetine in the treatment of obsessive compulsive disorder. Methods： In our hospital 54 patients with obsessive compulsive disorder were collected from February 2015 to February 2017 and randomly divided into a control group with 27 cases treated with paroxetine, an observation group with 27 cases treated with escitalopram, and both groups were treated for 8 weeks. The symptom scores were evaluated by the obsessive compulsive rating scale and the Hamilton depression scale, and the effective rates of the two groups and the incidence of adverse reactions were compared. Results： The effective rate of the observation group was 77.78%（21/27）, that of the control group was 74.07%, and there was no significant difference between the two groups（P>0.05）. After 8 weeks, the symptom scores of the two groups were lower than those before treatment（P<0.05）, especially at first week after treatment, the score of the observation group was lower than that of the control group（P<0.05）. The incidences of adverse reactions were 11.11%（3/27） in the observation group and 33.33%（9/27） in the control group, and the difference between the two groups was statistically significant（P<0.05）. Conclusion： The effect of escitalopram and paroxetine was better in the treatment of obsessive compulsive disorder patients, but escitalopram works faster, its safety is higher, and the patients have fewer adverse reactions, which is worthy of popularization and application.
KEY WORDS obsession； escitalopram； paroxetine； medication effect
強迫症是精神疾病的一种,病情容易反复发作,患者临床表现出反复强迫观念和强迫行为,终身发病率达1%～3%[1].有研究显示强迫症发病和人格有着密切的关系,多和其他精神疾病（抑郁、焦虑、抽动）合并,不仅影响患者的生活质量,而且加重患者的家庭负担和经济负担[2].强迫症临床主要用5-羟色胺再摄取抑郁剂治疗,可以有效改善患者的抑郁症状和强迫症状[3].本研究应用艾司西酞普兰治疗强迫症患者,疗效更为理想,安全性较好,现报道如下.
帕罗西汀论文参考资料：
结论：艾司西酞普兰和帕罗西汀治疗强迫症疗效比较为关于帕罗西汀方面的论文题目、论文提纲、盐酸帕罗西汀多少钱论文开题报告、文献综述、参考文献的相关大学硕士和本科毕业论文。
