原创《大面积烧伤患者围手术期乌司他丁对心肌保护作用》：该文是关于乌司他丁论文范文，为你的论文写作提供相关论文资料参考。
【摘 要】 目的 探讨大面积烧伤患者围手术期使用乌司他丁对心肌的保护作用.方法 66例进行手术治疗的大面积烧伤患者作为研究对象, 随机分为观察组和对照组, 每组33例.两组患者入院后均给予常规方法进行治疗, 观察组在以上治疗的基础上加用乌司他丁注射液治疗.治疗前及治疗4、7 d时测定两组氨基末端脑钠肽前体（NT-proBNP）和心型脂肪酸结合蛋白（h-FABP）水平, 并进行组间比较.结果 两组治疗前血浆NT-proBNP比较差异无统计学意义（P>0.05）；治療4 d时两组血浆NT-proBNP达到峰值, 且观察组血浆NT-proBNP（421.4±38.4）ng/ml明显低于对照组（592.5±36.1）ng/ml,
差异具有统计学意义（P<0.01）；治疗7 d时两组血浆NT-proBNP均有降低, 且观察组血浆NT-proBNP
（136.2±28.1）ng/ml明显低于对照组（301.1±29.5）ng/ml, 差异具有统计学意义（P<0.01）.两组治疗前血浆h-FABP比较差异无统计学意义（P>0.05）；治疗4 d时两组血浆h-FABP达到峰值, 且观察组血浆h-FABP（19.15±3.37）ng/ml明显低于对照组（23.83±3.01）ng/ml, 差异具有统计学意义（P<0.01）；治疗7 d时两组血浆h-FABP均有降低, 且观察组血浆h-FABP（2.09±0.41）ng/ml明显低于对照组（5.91±0.37）ng/ml,
差异具有统计学意义（P<0.01）.结论 大面积烧伤患者围手术期使用乌司他丁可以减轻心肌损伤, 有利于患者恢复.
【关键词】 大面积烧伤；乌司他丁；心肌
DOI：10.14163/j.cnki.11-5547/r.2018.01.045
【Abstract】 Objective To discuss the protective effect of ulinastatin on the myocardium in patients with large area burns during the perioperative period. Methods A total of 66 patients with large area burns undergoing surgical treatment as study subjects were randomly divided into observation group and control group, with 33 cases in each group. Both groups was treated with conventional therapy, and the observation group was also treated with ulinastatin injection. The levels of N-terminal pro brain natriuretic peptide （NT-proBNP） and heart type fatty acid binding protein （h-FABP） before and after treatment for 4 and 7 d in two groups were measured and compared. Results Both groups had no statistically significant difference in plasma NT-proBNP before treatment （P>0.05）. After 4 d of treatment, the plasma NT-proBNP reached its peak value in the two groups, and the observation group had obviously lower plasma NT-proBNP as （421.4±38.4） ng/ml than （592.5±36.1） ng/ml in the control group. Their difference was statistically significant （P<0.01）. After 7 d of treatment, both groups had lower plasma NT-proBNP, and the observation group had obviously lower plasma NT-proBNP as （136.2±28.1） ng/ml than （301.1±29.5） ng/ml in the control group. The difference was statistically significant （P<0.01）. Both groups had no statistically significant difference in plasma h-FABP before treatment （P>0.05）. After 4 d of treatment, the plasma h-FABP reached its peak value in the two groups, and the observation group had obviously lower plasma h-FABP as （19.15±3.37） ng/ml than （23.83±3.01） ng/ml in the control group. The difference was statistically significant （P<0.01）. After 7 d of treatment, both groups had lower plasma h-FABP, and the observation group had obviously lower plasma h-FABP as （2.09±0.41） ng/ml than （5.91±0.37） ng/ml in the control group. The difference was statistically significant （P<0.01）. Conclusion Application of ulinastatin for patients with large area burns during the perioperative period can relieve the injury of the myocardium and be beneficial to the recovery of the patients.
乌司他丁论文参考资料：
结论：大面积烧伤患者围手术期乌司他丁对心肌保护作用为关于对不知道怎么写乌司他丁论文范文课题研究的大学硕士、相关本科毕业论文生长抑素论文开题报告范文和文献综述及职称论文的作为参考文献资料下载。
